Results for: Headache with Fatigue
Emergency Warning Signs
Call 911 or go to the emergency room immediately if you experience:
- Difficulty breathing or shortness of breath
- Chest pain or pressure
- Sudden numbness or weakness in face, arm, or leg
- Sudden confusion or trouble speaking
- Severe allergic reaction (swelling, difficulty swallowing)
- Heavy bleeding that won't stop
- Loss of consciousness
- Signs of stroke (face drooping, arm weakness, speech difficulty)
20 Possible Conditions
These conditions are listed by likelihood based on the symptom. This is not a diagnosis.
Tension-type headache
A common headache caused by muscle tension in the neck and scalp, often accompanied by mild fatigue.
Migraine
A neurological disorder characterized by throbbing head pain, sensitivity to light, and often preceded or followed by fatigue.
Sinusitis
Inflammation of the sinus cavities that can cause pressure headaches and a feeling of tiredness.
Influenza (flu)
A viral infection that typically presents with fever, body aches, headache, and pronounced fatigue.
COVID-19 infection
SARS‑CoV‑2 infection often includes headache, fatigue, and a range of other systemic symptoms.
Anemia
Reduced red blood cell count leads to decreased oxygen delivery, causing headaches and persistent fatigue.
Hypothyroidism
Underactive thyroid gland can cause generalized weakness, fatigue, and occasional headaches.
Sleep apnea
Interrupted breathing during sleep results in poor rest, leading to morning headaches and daytime fatigue.
Depression
Mood disorder that frequently includes physical symptoms such as headache and low energy.
Chronic fatigue syndrome (Myalgic Encephalomyelitis)
A complex disorder marked by profound fatigue and often accompanied by headaches and cognitive difficulties.
Mononucleosis
EBV infection causing sore throat, swollen lymph nodes, headache, and marked fatigue.
Dehydration
Insufficient fluid intake can lead to headache, dizziness, and a feeling of exhaustion.
Medication overuse headache
Frequent use of analgesics can paradoxically cause daily headaches and fatigue.
Hypertension (high blood pressure)
Elevated blood pressure may present with dull headaches and a sense of tiredness, especially if uncontrolled.
Concussion
Mild traumatic brain injury often results in headache, confusion, and post‑injury fatigue.
Post‑concussive syndrome
Persistent symptoms after a concussion, including headache and prolonged fatigue lasting weeks to months.
Lyme disease
Tick‑borne infection that can cause headache, joint pain, and debilitating fatigue if untreated.
Vitamin B12 deficiency
Lack of B12 leads to neurological symptoms such as headache, weakness, and chronic fatigue.
Meningitis (bacterial)
Serious infection of the meninges presenting with severe headache, neck stiffness, fever, and profound fatigue.
Brain tumor
Neoplastic growth can cause persistent headache and progressive fatigue, often accompanied by neurological deficits.
When to Seek Emergency Care
While many conditions can be managed with home care or a doctor's visit, some situations require immediate medical attention. Seek emergency care if:
Heart-Related
Chest pain, rapid heartbeat, or shortness of breath
Brain-Related
Severe headache, confusion, or sudden vision changes
High Fever
Fever above 103°F (39.4°C) or fever with stiff neck
Severe Bleeding
Uncontrolled bleeding or coughing up blood
Medical Disclaimer
Medical Disclaimer: The information provided on this website is for general informational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website. If you think you may have a medical emergency, call your doctor, go to the emergency department, or call 911 immediately.
Sources: Mayo Clinic, WebMD, CDC, NIH